The SHRINE adapter received a malformed xml response from the CRC that could not interpret.
A SHRINE adapter expects XML messages that comply with the i2b2 messaging protocol. If the CRC sends malformed XML then SHRINE cannot interpret it.
If you are a user, supply all details to your site admin who can work with the adapter admin to resolve the issue.
If you are the adapter admin, examine the details, especially the response body, to help determine what is wrong. The response body is very likely a message from Apache that will give you some insight into the problem. Please share what you learn, plus the summary, description, and all details to firstname.lastname@example.org so that we can investigate, help solve the problem, and provide better diagnostics in a future release.