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Building on the I2B2 platform, SHRINE enables federated queries across enables federated queries across many independently operated patient databases.
With over 60 sites participating in the I2B2 National Center for Biomedical Computing, there is now a rare opportunity to conduct regional and national health studies.

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Building on the success of the SPIN the SPIN federated query system system [Paper], SHRINE provides a scalable query and aggregation mechanism.
See our article in JAMIA for details on the federated credentialing system, scalable peer-to-peer architecture, and secure logging and auditing.