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The local I2B2 PM cell could not be reached at the configured URL.

Explanation

The most likely cause is that SHRINE is misconfigured to interact with something other than the i2b2 PM cell, or that the PM cell is malfunctioning.

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If you are a site admin, check shrine.conf, ensure that the URL for the PM cell is correct, and ensure that i2b2 is runningresponsive and reachable as configured.