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Do not install SHRINE and i2b2 on the same operating system. Both SHRINE's Tomcat and i2b2's Wildfly servers are optimized to make maximum use of the operating system's resources. Either can starve the other for processing time or memory to the point of stalling both systems.

We strongly advise that you avoid placing SHRINE behind an application proxy. Misconfigured application proxies frequently interfere with SHRINE's networking needs. They offer no benefits in a SHRINE network and make troubleshooting very difficult. If you must run an application proxy, we ask that you configure your proxy to not intercept or modify any of SHRINE's network traffic.